Early Signs Of Alzheimers Disease

Experts estimate about 500,000 cases of Alzheimer's Disease or dementia in people that's in their 30s, 40s, and 50s.

Signs of Alzheimers Disease, Treatments And Care

Most of us know that Alzheimer's disease is a progressive and fatal brain disorder.

It was named after a German doctor named Alois Alzheimer.

He was the first one to describe the disease in 1906. Scientists have learned many new things about Alzheimer's Disease. As many as 5.3 millions of Americans live with the disease. Alzheimer's starts by destroying the brain cells that in change cause memory loss and many other problems related to thinking.

It also affects the behavior of the person enough to affect social life, hobbies work and the communication and the relationship the affected person have with family members, friends and coworkers.

How do Alzheimer's affect the brain

Our brain changes as we age. Most of us notice some slowed thinking and some occasional problems remembering things, like where did I put the car keys or where did I put the cup I was using.

That is a normal part of aging and does not need to be confused with the signs of Alzheimers Disease.

Serious memory loss and major changes in the way our mind works are not a normal part of aging. At the beginning of the disease individuals may need minimal assistance with simple daily tasks. At the time of the diagnosis the individual may have progressed beyond the early stage of the disease. Experts estimate about 500,000 cases of Alzheimer's Disease or dementia in people that's in their 30s, 40s, and 50s. Alzheimer's gets worst over time and at the end its fatal.

Signs of Alzheimers Disease

Difficulty completing familiar tasks at home, at work or at leisure, Memory changes that disrupt daily life, Trouble understanding visual images and spatial relationships, Confusion with time or place, Problems with words in speaking or writing, Decreased or poor judgment,Misplacing things and losing the ability to retrace steps,Changes in mood and personality, Withdrawal from work or social activities.

There may be other signs of alzheimer disease. Consult your family doctor for information.

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There is no cure for the disease but currently there are treatments for the symptoms. Health professionals usually divide the symptoms and signs of alzheimers Disease into two different categories.

1). Cognitive- Affects memory, judgment, ability to pay attention, language and thought process.

2). Behavioral and psychiatric symptoms that affect the way we feel and act.

Treatments for cognitive symptoms

These drugs affect the activity of two different chemicals involved in carrying message.

1).Cholinesterase inhibitors: These inhibitors prevent breakdown of acetylcholine an important chemical messenger for learning and memory.

These drugs support communication of nerve cells by keeping high levels of acetylcholine.

Three cholinesterase inhibitors are commonly prescribed:

Donepezil (Aricept), approved to treat all stages of Alzheimer's disease.

Rivastigmine (Exelon), approved to treat mild to moderate Alzheimer's.

Galantamine (Razadyne), approved to treat mild to moderate Alzheimer's.

2). Memantine: Works by regulating the activity of glutamate, a different messenger chemical involved in learning and memory.

It was approved in 2003 for treatment of moderate to Severe Alzheimer's Disease. Is currently the only drug of its type approved to treat Alzheimer's.

Temporarily delays worsening of signs of Alzheimers Disease in some people. Many experts consider its degree of benefit is similar to the cholinesterase inhibitors.

Memantine is generally well-tolerated. Common adverse drug reactions (¡Ý1% of patients) include: confusion, dizziness, drowsiness, headache, insomnia, agitation, and/or hallucinations. Less common adverse effects include: vomiting, anxiety hypertonia, cystitis, and increased libido. On the other hand; it has been reported to induce reversible neurological impairment in multiple sclerosis, that led to stop an ongoing clinical trial.(wikipedia)

Memantine was first synthesized and patented by Eli Lilly and Company in 1968 (as cited in the Merck Index), and then developed by Merz in collaboration with Neurobiological Technologies, Inc. and licensed to Forest for the U.S. and Lundbeck for selected European and international markets.(wikipedia)